Pentane

Pentane

SCHEMBL28008463

CCCCC.Oc1cccc(-c2cccc(O)c2)c1

nearest known ligand 0.62

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 9/20 0.62
HSD17B2 P37059 9/20 0.62
CYP3A4 P08684 3/20 0.62
CYP2C9 P11712 2/20 0.62
MGLL Q99685 1/20 0.53
ESR1 P03372 2/20 0.52
ESR2 Q92731 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2B6 P20813 1/20 0.52
CYP2C19 P33261 1/20 0.52
CA12 O43570 1/20 0.48
ALDH1A1 P00352 1/20 0.48
CA2 P00918 1/20 0.48
LMNA P02545 1/20 0.48
CA5A P35218 1/20 0.48
CA9 Q16790 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CA14 Q9ULX7 1/20 0.48
CA5B Q9Y2D0 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Pentane SCHEMBL28008464 0.92 HSD17B1 (0.73) HSD17B1HSD17B2CYP3A4CYP2C9MGLL
Propane SCHEMBL5843489 0.88 HSD17B1 (0.71) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Alcohol SCHEMBL9461730 0.86 HSD17B1 (0.68) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Alcohol SCHEMBL23879308 0.84 HSD17B1 (0.65) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Resorcinol SCHEMBL23248736 0.83 CYP3A4 (0.63) CYP3A4CA12ALDH1A1CA2LMNA
SCHEMBL29551999 0.83 HSD17B1 (0.88) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL69369 0.83 HSD17B1 (0.88) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Propane SCHEMBL27565820 0.82 HSD17B1 (0.70) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
Alcohol SCHEMBL23879306 0.82 HSD17B1 (0.62) HSD17B1HSD17B2CYP3A4CYP2C9ESR1
SCHEMBL28352089 0.80 PTGS2 (0.61) HSD17B1HSD17B2CYP3A4CYP2C9MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102821860-B Process for assembling elements contacting biological substances OLIVETTI PERSONAL COMP SPA 2015-04-08 CN disclosed