Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1625037 | 0.80 | PTGER4 (0.38) | MEN1KMT2APOLBPABPC1 | |
| SCHEMBL7017841 | 0.79 | ALDH1A1 (0.41) | HPGDMEN1KMT2AALDH1A1POLB | |
| SCHEMBL1625038 | 0.78 | PTGER4 (0.36) | MEN1KMT2A | |
| SCHEMBL1625198 | 0.78 | PTGER4 (0.36) | MEN1KMT2A | |
| SCHEMBL28008635 | 0.74 | MEN1 (0.44) | TSHRMEN1KMT2AMAPK1POLB | |
| SCHEMBL7015251 | 0.74 | HSD17B10 (0.37) | KDM4ETSHRHSD17B10HPGDMEN1 | |
| SCHEMBL27597640 | 0.74 | GLO1 (0.36) | KDM4ETSHR | |
| SCHEMBL6385097 | 0.74 | POLB (0.36) | KDM4ETSHRHPGDMEN1KMT2A | |
| SCHEMBL7016110 | 0.73 | — | — | |
| SCHEMBL7018959 | 0.73 | MEN1 (0.43) | KDM4EMEN1KMT2AALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101967146-B | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents | RAQUALIA PHARMA INC | 2015-04-08 | — | — | CN | disclosed |