Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR4 | P46093 | 3/20 | 0.41 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28008299 | 0.86 | GPR4 (0.32) | GPR4AGTR1AGTR2 | |
| SCHEMBL1625625 | 0.84 | GPR4 (0.43) | GPR4CRHR1AGTR2 | |
| SCHEMBL1625432 | 0.84 | GPR4 (0.46) | GPR4CRHR1KCNH2HRH3AGTR2 | |
| SCHEMBL1624892 | 0.84 | GPR4 (0.43) | GPR4CRHR1KCNH2HRH3 | |
| SCHEMBL27579860 | 0.82 | GPR4 (0.45) | GPR4CRHR1KCNH2HRH3 | |
| SCHEMBL27618343 | 0.80 | GPR4 (0.40) | GPR4KCNH2HRH3 | |
| SCHEMBL7626311 | 0.78 | GPR4 (0.39) | GPR4 | |
| SCHEMBL1625041 | 0.78 | AGTR1 (0.41) | GPR4AGTR1AGTR2 | |
| SCHEMBL7626314 | 0.76 | GPR4 (0.38) | GPR4 | |
| SCHEMBL3953485 | 0.74 | GPR4 (0.45) | GPR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101967146-B | Aryl or heteroaryl fused imidazole compounds as anti-inflammatory and analgesic agents | RAQUALIA PHARMA INC | 2015-04-08 | — | — | CN | disclosed |