Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 2/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | PRCP | P42785 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27445281 | 0.65 | — | — | |
| SCHEMBL1718039 | 0.65 | ALOX15 (0.43) | AKR1C3AKR1C1SMN1; SMN2GRIK2GBA1 | |
| SCHEMBL28833784 | 0.65 | ALOX15 (0.43) | AKR1C3AKR1C1SMN1; SMN2GRIK2GBA1 | |
| SCHEMBL1718035 | 0.65 | ALOX15 (0.43) | AKR1C3AKR1C1SMN1; SMN2GRIK2GBA1 | |
| SCHEMBL1718034 | 0.65 | ALOX15 (0.43) | AKR1C3AKR1C1SMN1; SMN2GRIK2GBA1 | |
| SCHEMBL6635115 | 0.65 | ALOX15 (0.43) | AKR1C3AKR1C1SMN1; SMN2GRIK2GBA1 | |
| SCHEMBL28833830 | 0.65 | ALOX15 (0.43) | AKR1C3AKR1C1SMN1; SMN2GRIK2GBA1 | |
| SCHEMBL27807937 | 0.63 | GBA1 (0.43) | AKR1C3AKR1C1SMN1; SMN2GBA1TSHR | |
| SCHEMBL199463 | 0.62 | SLC1A2 (0.47) | AKR1C3AKR1C1 | |
| SCHEMBL4780406 | 0.62 | SLC1A2 (0.47) | AKR1C3AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640843-A | 1-(cycloalkyl-carbonyl)proline derivative | DAINIPPON SUMITOMO PHARMA CO | 2015-05-20 | — | — | CN | disclosed |