Trolamine

Trolamine

SCHEMBL2800899

OCCN(CCO)CCO.OCCN(CCO)CCO.OCCN(CCO)CCO.OCCN(CCO)CCO.[Ti]

nearest known ligand 0.44

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.44
KDM4E B2RXH2 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
ALOX15 P16050 1/20 0.39
HPGD P15428 2/20 0.36
MAPK1 P28482 2/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2C9 P11712 1/20 0.36
HIF1A Q16665 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
TSHR P16473 1/20 0.33
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trolamine SCHEMBL216806 1.00 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL15329505 1.00 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL28070293 1.00 MAPT (0.44) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL27733888 0.96 MAPT (0.41) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL27829702 0.96 MAPT (0.41) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL15845959 0.95 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL4748243 0.95 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL434089 0.95 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
Trolamine SCHEMBL1146 0.95 MAPT (0.47) MAPTKDM4ESMN1; SMN2ALOX15HPGD
SCHEMBL23528233 0.91 MAPT (0.46) MAPTKDM4ESMN1; SMN2ALOX15HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7732382-B2 Cross-linking composition and method of use E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-08 US claimed
US-20070191233-A1 Cross-linking composition and method of use DORF KETAL SPECIALITY CATALYSTS, LLC 2007-08-16 US claimed
US-7732382-B2 Cross-linking composition and method of use E.I. DU PONT DE NEMOURS AND COMPANY (US) 2010-06-08 US disclosed
US-20070187098-A1 Permeable zone and leak plugging using cross-linking composition comprising delay agent E. I. DU PONT DE NEMOURS AND COMPANY 2007-08-16 US disclosed
US-20070187102-A1 Hydraulic fracturing methods using cross-linking composition comprising delay agent E. I. DU PONT DE NEMOURS AND COMPANY 2007-08-16 US disclosed
US-20070191233-A1 Cross-linking composition and method of use DORF KETAL SPECIALITY CATALYSTS, LLC 2007-08-16 US disclosed
US-4444862-A Electrophotographic photosensitive materials having layer of organic metal compound FUJI XEROX CO., LTD. (JP) 1984-04-24 US disclosed
US-RE29213-E TRIMELLITIC ANHYDRIDE, DIISOCYANATE, GLYCINE DERIVATIVE SCHENECTADY CHEMICALS, INC. (US) 1977-05-10 US disclosed