Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.43 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | CSF1R | P07333 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1532302 | 0.83 | LMNA (0.48) | GAAALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL4460275 | 0.83 | CA12 (0.49) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL4460272 | 0.83 | CA12 (0.49) | GAAALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL1531518 | 0.82 | MEN1 (0.44) | GAAALDH1A1MAPTHSD17B10SYK | |
| SCHEMBL6249680 | 0.79 | SYK (0.56) | GAAALDH1A1MAPTHSD17B10SYK | |
| SCHEMBL7714036 | 0.78 | TP53 (0.50) | GAAALDH1A1MAPTHSD17B10MEN1 | |
| SCHEMBL16743153 | 0.77 | SYK (0.59) | SYK | |
| SCHEMBL11651437 | 0.76 | MAPT (0.49) | GAAALDH1A1MAPTHSD17B10SYK | |
| SCHEMBL11588598 | 0.75 | ITGB3 (0.52) | GAAMAPTHSD17B10CYP1A2MEN1 | |
| SCHEMBL27851104 | 0.75 | MAPT (0.50) | GAAALDH1A1MAPTHSD17B10CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101412709-B | Morpholinyl containing benzimidazoles as inhibitors of respiratory syncytial virus replication | TIBOTEC PHARM LTD | 2015-03-25 | — | — | CN | disclosed |