Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28009398 | 0.85 | MAPT (0.47) | ALDH1A1MAPTLMNATDP1FKBP1A | |
| SCHEMBL28009386 | 0.82 | SHMT2 (0.39) | ALDH1A1MAPTLMNATP53HTT | |
| SCHEMBL17600397 | 0.81 | MAPT (0.47) | ALDH1A1MAPTLMNATDP1FKBP1A | |
| SCHEMBL16114904 | 0.81 | MAPT (0.47) | ALDH1A1MAPTLMNATDP1FKBP1A | |
| SCHEMBL27788686 | 0.75 | TDP1 (0.46) | ALDH1A1MAPTLMNATDP1SMN1; SMN2 | |
| SCHEMBL10173636 | 0.72 | ALDH1A1 (0.45) | ALDH1A1MAPTLMNATDP1SMN1; SMN2 | |
| SCHEMBL6796594 | 0.71 | MAPT (0.48) | ALDH1A1MAPTLMNAFKBP1ASMN1; SMN2 | |
| SCHEMBL15623039 | 0.71 | PTPN1 (0.47) | ALDH1A1MAPTLMNATDP1FKBP1A | |
| SCHEMBL15623036 | 0.71 | PTPN1 (0.47) | ALDH1A1MAPTLMNATDP1FKBP1A | |
| SCHEMBL15623037 | 0.69 | PTPN1 (0.46) | ALDH1A1MAPTLMNATDP1FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104640843-A | 1-(cycloalkyl-carbonyl)proline derivative | DAINIPPON SUMITOMO PHARMA CO | 2015-05-20 | — | — | CN | disclosed |