SCHEMBL28009449

SCHEMBL28009449

Cc1cc(Cc2ccccc2)c(Cc2ccccc2)c(Cc2ccccc2)c1Cc1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.45
BCL2L1 Q07817 1/20 0.45
CALM1 P0DP23 1/20 0.42
IDH1 O75874 1/20 0.41
CYP3A4 P08684 3/20 0.41
CYP2D6 P10635 2/20 0.41
CYP2C19 P33261 2/20 0.41
TSHR P16473 1/20 0.41
ALOX5 P09917 1/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
LDHA P00338 2/20 0.39
LDHB P07195 2/20 0.39
NQO1 P15559 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C9 P11712 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
HTR2A P28223 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28593839 0.85 BCL2 (0.54) BCL2BCL2L1CALM1IDH1CYP3A4
Fluoride SCHEMBL28569108 0.83 BCL2 (0.52) BCL2BCL2L1CALM1IDH1CYP3A4
SCHEMBL9063880 0.82 IDH1 (0.46) BCL2BCL2L1CALM1IDH1CYP3A4
SCHEMBL11247248 0.81 BCL2 (0.42) BCL2BCL2L1CALM1IDH1CYP3A4
SCHEMBL8092285 0.81 BCL2 (0.54) BCL2BCL2L1CALM1CYP3A4CYP2D6
SCHEMBL11247239 0.79 IDH1 (0.41) BCL2BCL2L1CALM1IDH1MEN1
SCHEMBL28062659 0.78 IDH1 (0.35) BCL2BCL2L1CALM1IDH1CYP3A4
SCHEMBL11748855 0.77 BCL2 (0.50) BCL2BCL2L1CALM1CYP3A4CYP2D6
SCHEMBL8100218 0.77 CALM1 (0.55) BCL2BCL2L1CALM1IDH1NQO1
SCHEMBL7819859 0.77 CALM1 (0.48) BCL2BCL2L1CALM1IDH1CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104513126-B The preparation method and application of the many benzyl toluene of a kind of alkyl or alkyl dibenzyl toluene ZHAO CHAOHUA (CN) 2016-02-03 CN claimed
CN-104513126-A Preparation method and applications of alkyl multi-benzyl toluene or alkyl dibenzyl toluene ZHAO CHAOHUA 2015-04-15 CN claimed
CN-104513126-B The preparation method and application of the many benzyl toluene of a kind of alkyl or alkyl dibenzyl toluene ZHAO CHAOHUA (CN) 2016-02-03 CN disclosed
CN-104513126-A Preparation method and applications of alkyl multi-benzyl toluene or alkyl dibenzyl toluene ZHAO CHAOHUA 2015-04-15 CN disclosed