Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.54 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.54 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.52 |
| ▸ | LDHA | P00338 | 3/20 | 0.51 |
| ▸ | LDHB | P07195 | 3/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11748855 | 0.95 | BCL2 (0.50) | BCL2BCL2L1CALM1LDHALDHB | |
| SCHEMBL31154605 | 0.88 | BCL2 (0.59) | BCL2BCL2L1LDHALDHBALOX5 | |
| SCHEMBL22054607 | 0.85 | BCL2 (0.73) | BCL2BCL2L1LDHALDHBALOX5 | |
| Ammonia Solution, Strong SCHEMBL27938008 | 0.85 | CYP11B1 (0.46) | BCL2BCL2L1CALM1LDHALDHB | |
| SCHEMBL20159665 | 0.83 | ALDH1A1 (0.55) | BCL2BCL2L1CALM1LDHALDHB | |
| SCHEMBL12816172 | 0.83 | LDHA (0.41) | BCL2BCL2L1CALM1LDHALDHB | |
| SCHEMBL12817360 | 0.83 | LDHA (0.41) | BCL2BCL2L1CALM1LDHALDHB | |
| SCHEMBL1276089 | 0.82 | CYP3A4 (0.57) | BCL2BCL2L1CALM1LDHALDHB | |
| SCHEMBL3301748 | 0.82 | CYP3A4 (0.53) | BCL2BCL2L1CALM1LDHALDHB | |
| SCHEMBL4455072 | 0.82 | CALM1 (0.50) | BCL2BCL2L1CALM1LDHALDHB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708077-B1 | Diamino compounds and methods for preparing them | CHISSO CORP (JP) | 2000-12-27 | — | — | EP | disclosed |
| US-5663440-A | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0708077-A1 | Diamino compounds and methods for preparing them | CHISSO CORPORATION (JP) | 1996-04-24 | — | — | EP | disclosed |
| US-4214108-A | TITANIUM HALIDE AND ALKYLALUMINUM HALIDE CATALYST | CHEMISCHE WERKE HULS AKTIENGESELLSCHAFT (DE) | 1980-07-22 | — | — | US | disclosed |