Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19004724 | 0.76 | TSHR (0.40) | TSHR | |
| SCHEMBL109285 | 0.76 | TSHR (0.40) | TSHR | |
| SCHEMBL9764128 | 0.76 | TSHR (0.33) | TSHR | |
| SCHEMBL3336438 | 0.76 | ACE2 (0.35) | TSHR | |
| SCHEMBL17150576 | 0.75 | CA2 (0.58) | TSHRCA2MAPK1 | |
| SCHEMBL7191105 | 0.75 | CA2 (0.58) | TSHRCA2MAPK1 | |
| SCHEMBL9763679 | 0.75 | — | — | |
| SCHEMBL24072902 | 0.73 | CA2 (0.59) | TSHRCA2MAPK1 | |
| SCHEMBL1402358 | 0.73 | — | — | |
| SCHEMBL6716505 | 0.72 | CA2 (0.43) | CA2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010117796-A2 | PROCESSES FOR THE PREPARATION OF ALPHA-CHLOROKETONES FROM CARBOXYLIC ACIDS | CODEXIS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| EP-1180765-B1 | Optical recording medium and porphycene compound | MITSUI CHEMICALS INC (JP) | 2005-04-06 | — | — | EP | disclosed |
| US-6087360-A | TREATING PATIENTS WITH ENDOTHELIN RELATED DISORDERS | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2000-07-11 | — | — | US | disclosed |