Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109285 | 1.00 | TSHR (0.40) | TSHRLMNA | |
| SCHEMBL108583 | 0.89 | — | — | |
| SCHEMBL18600550 | 0.89 | — | — | |
| SCHEMBL1270793 | 0.86 | LMNA (0.53) | TSHRLMNA | |
| SCHEMBL30697989 | 0.86 | LMNA (0.53) | TSHRLMNA | |
| SCHEMBL25198937 | 0.86 | LMNA (0.53) | TSHRLMNA | |
| SCHEMBL21925388 | 0.86 | TSHR (0.50) | TSHRLMNA | |
| SCHEMBL24224784 | 0.86 | TSHR (0.50) | TSHRLMNA | |
| SCHEMBL1093727 | 0.86 | ALDH1A1 (0.32) | TSHR | |
| SCHEMBL7749361 | 0.84 | TSHR (0.56) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170172993-A1 | Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy | ABBVIE INC. | 2017-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170172993-A1 | Aminotetraline and aminoindane derivatives, pharmaceutical compositions containing them, and their use in therapy | AADAT, BCAT1, GFPT1 | TSHR 3516/4885LMNA 3087/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.