Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
| ▸ | ELANE | P08246 | 1/20 | 0.48 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28009569 | 1.00 | MMP8 (0.52) | MMP8ELANEHPRT1CTSLCTSB | |
| SCHEMBL15380809 | 0.88 | ATM (0.56) | — | |
| SCHEMBL25301790 | 0.88 | ATM (0.56) | — | |
| SCHEMBL30862473 | 0.87 | BACE1 (0.51) | — | |
| Hydrochloric Acid SCHEMBL7600821 | 0.87 | ATM (0.55) | — | |
| Hydrochloric Acid SCHEMBL7600824 | 0.87 | ATM (0.55) | — | |
| Ethyl Acetate SCHEMBL8046014 | 0.87 | CTSL (0.47) | MMP8CTSLCTSBCPA1 | |
| Ethyl Acetate SCHEMBL8046018 | 0.87 | CTSL (0.47) | MMP8CTSLCTSBCPA1 | |
| SCHEMBL28219511 | 0.85 | CTSL (0.45) | MMP8CTSLCTSBCPA1 | |
| SCHEMBL28209567 | 0.84 | CTSL (0.49) | CTSLCTSBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083693-A | The N phthalyl synthesis technique to (dihydroxy ethyl) amino L phenylalanine ethyl ester | 王健 | 2016-11-09 | — | — | CN | claimed |
| CN-107935875-A | A kind of synthetic method of melphalan | 兆科药业（广州）有限公司 | 2018-04-20 | — | — | CN | disclosed |
| CN-106083693-A | The N phthalyl synthesis technique to (dihydroxy ethyl) amino L phenylalanine ethyl ester | 王健 | 2016-11-09 | — | — | CN | disclosed |
| CN-103228631-B | Kat II inhibitors | PFIZER | 2015-04-29 | — | — | CN | disclosed |