Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 9/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28009777 | 1.00 | DHODH (0.35) | DHODHOPRM1MAOB | |
| SCHEMBL28818537 | 0.99 | DHODH (0.36) | DHODHOPRM1MAOB | |
| SCHEMBL3908785 | 0.88 | OPRM1 (0.45) | OPRM1 | |
| SCHEMBL3897938 | 0.88 | OPRM1 (0.45) | OPRM1 | |
| SCHEMBL3900975 | 0.88 | OPRM1 (0.45) | OPRM1 | |
| SCHEMBL3900984 | 0.86 | OPRM1 (0.46) | DHODHOPRM1 | |
| SCHEMBL3903713 | 0.81 | TYMP (0.39) | DHODHOPRM1MAOB | |
| SCHEMBL3903710 | 0.81 | TYMP (0.39) | DHODHOPRM1MAOB | |
| SCHEMBL10048510 | 0.81 | ALDH1A1 (0.40) | DHODH | |
| SCHEMBL28009304 | 0.80 | DHODH (0.47) | DHODHMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104582694-A | Dihydroorotic acid dehydrogenase inhibitor | NAI INC | 2015-04-29 | — | — | CN | disclosed |