Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.54 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | SLC5A1 | P13866 | 1/20 | 0.46 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10900609 | 0.90 | LMNA (0.58) | TDP1CYP4F2CYP4A11LMNAL3MBTL1 | |
| SCHEMBL17250903 | 0.88 | TDP1 (0.61) | TDP1CYP4F2CYP4A11L3MBTL1APP | |
| SCHEMBL22435402 | 0.87 | NPC1 (0.50) | TDP1CYP4F2CYP4A11LMNAL3MBTL1 | |
| SCHEMBL28241121 | 0.87 | TDP1 (0.56) | TDP1CYP4F2CYP4A11LMNAL3MBTL1 | |
| SCHEMBL752665 | 0.86 | CYP4F2 (0.72) | TDP1CYP4F2CYP4A11LMNACYP1A2 | |
| SCHEMBL24988200 | 0.85 | CYP4F2 (0.60) | TDP1CYP4F2CYP4A11LMNAL3MBTL1 | |
| Hydrochloric Acid SCHEMBL6982675 | 0.85 | CYP4F2 (0.70) | TDP1CYP4F2CYP4A11LMNACYP1A2 | |
| SCHEMBL1587175 | 0.85 | L3MBTL1 (0.71) | TDP1CYP4F2CYP4A11LMNAL3MBTL1 | |
| SCHEMBL10840858 | 0.85 | TDP1 (0.58) | TDP1CYP4F2CYP4A11LMNAL3MBTL1 | |
| SCHEMBL17250899 | 0.85 | TDP1 (0.58) | TDP1CYP4F2CYP4A11LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104529800-B | Preparation method of trans-4-dimethylaminocrotonic acid and its salt | 重庆威鹏药业有限公司 | 2017-01-25 | — | — | CN | claimed |
| CN-104529800-B | Preparation method of trans-4-dimethylaminocrotonic acid and its salt | 重庆威鹏药业有限公司 | 2017-01-25 | — | — | CN | disclosed |
| CN-104529800-A | Preparation method of trans-4-dimethylaminocrotonic acid and its salt | CHONGQING WEIPENG PHARMACEUTICAL CO LTD | 2015-04-22 | — | — | CN | disclosed |