Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.65 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.58 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.58 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10263771 | 0.82 | POLB (0.69) | POLBRAB9ANPC1SMN1; SMN2KMT2A | |
| SCHEMBL5398772 | 0.80 | HDAC6 (0.53) | POLBSLC6A4SLC6A3SLC6A2TDP1 | |
| SCHEMBL8378911 | 0.80 | POLB (0.71) | POLBSLC6A4SLC6A3SLC6A2TDP1 | |
| SCHEMBL9933780 | 0.79 | POLB (0.65) | POLBSLC6A4SLC6A3SLC6A2TDP1 | |
| SCHEMBL28009527 | 0.79 | POLB (0.65) | POLBSLC6A4SLC6A2RAB9ANPC1 | |
| SCHEMBL3896275 | 0.79 | POLB (1.00) | POLBRAB9ANPC1SMN1; SMN2CYP1A2 | |
| SCHEMBL14383993 | 0.79 | POLB (0.59) | POLBSLC6A4SLC6A3SLC6A2RAB9A | |
| SCHEMBL27445247 | 0.77 | POLB (0.72) | POLBSLC6A4RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15133705 | 0.77 | RAB9A (0.47) | POLBSLC6A4SLC6A3SLC6A2TDP1 | |
| SCHEMBL31645083 | 0.77 | POLB (0.43) | POLBSLC6A4SLC6A3SLC6A2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104892545-A | Method for synthesizing poly-substituted 2-aryl benzothiazoles by utilizing thiourea as sulphur source | UNIV NANJING SCIENCE & TECH | 2015-09-09 | — | — | CN | claimed |
| CN-104892545-A | Method for synthesizing poly-substituted 2-aryl benzothiazoles by utilizing thiourea as sulphur source | UNIV NANJING SCIENCE & TECH | 2015-09-09 | — | — | CN | disclosed |