Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.72 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | S100A4 | P26447 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3896275 | 0.85 | POLB (1.00) | POLBCYP3A4RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL22531853 | 0.81 | POLB (0.78) | POLBCYP3A4SLC6A4RAB9ASMN1; SMN2 | |
| SCHEMBL1118653 | 0.79 | POLB (0.52) | POLBCYP3A4SLC6A4RAB9AKMT2A | |
| SCHEMBL30231962 | 0.79 | POLB (0.52) | POLBCYP3A4SLC6A4RAB9AKMT2A | |
| SCHEMBL16242598 | 0.78 | POLB (0.87) | POLBCYP3A4SLC6A4RAB9ASMN1; SMN2 | |
| SCHEMBL8378911 | 0.78 | POLB (0.71) | POLBCYP3A4SLC6A4RAB9ASMN1; SMN2 | |
| SCHEMBL31282348 | 0.77 | POLB (0.55) | POLBCYP3A4SLC6A4RAB9ASMN1; SMN2 | |
| SCHEMBL16242699 | 0.77 | POLB (0.77) | POLBCYP3A4SLC6A4RAB9ASMN1; SMN2 | |
| SCHEMBL31051317 | 0.75 | POLB (0.56) | POLBCYP3A4SLC6A4RAB9ASMN1; SMN2 | |
| SCHEMBL6916799 | 0.75 | POLB (0.61) | POLBCYP3A4TSHRRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240262792-A1 | USP30 INHIBITORS AND USES THEREOF | VINCERE BIOSCIENCES, INC. | 2024-08-08 | — | — | US | disclosed |
| CN-1122803-A | Benzoxazolyl- and benzothiazolyloxazolidinones | BAYER AG (DE) | 1996-05-22 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240262792-A1 | USP30 INHIBITORS AND USES THEREOF | USP30, USP28, USP1 | POLB 2146/4885CYP3A4 3893/4885TSHR 3997/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.