SCHEMBL28010184

SCHEMBL28010184

C=CCOC(=O)CC(C1CCCCC1)(C1CCCCC1)C1CCCCC1

nearest known ligand 0.48

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
GAA P10253 1/20 0.48
CASP1 P29466 1/20 0.38
TSHR P16473 1/20 0.37
NPSR1 Q6W5P4 2/20 0.35
TDP1 Q9NUW8 1/20 0.34
MAPT P10636 3/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
CYP3A4 P08684 1/20 0.32
EPHX2 P34913 1/20 0.32
PKM P14618 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
LMNA P02545 1/20 0.30
CACNA1B Q00975 1/20 0.30
APBA1 Q02410 1/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19629 0.75 CASP1 (0.60) ALDH1A1GAACASP1TSHRTDP1
SCHEMBL21059 0.74 ALDH1A1 (0.51) ALDH1A1GAACASP1TSHRNPSR1
SCHEMBL873717 0.72 ALDH1A1 (0.61) ALDH1A1GAACASP1TSHRMAPT
SCHEMBL31147058 0.72 ALDH1A1 (0.44) ALDH1A1GAACASP1TSHRNPSR1
SCHEMBL19259363 0.72 ALDH1A1 (0.49) ALDH1A1GAACASP1TSHRTDP1
SCHEMBL11055019 0.72 ALDH1A1 (0.45) ALDH1A1GAACASP1TSHRNPSR1
SCHEMBL273853 0.71 ALDH1A1 (0.49) ALDH1A1GAACASP1TSHRNPSR1
SCHEMBL874452 0.71 ALDH1A1 (0.59) ALDH1A1GAACASP1TSHRMAPT
SCHEMBL28558880 0.71 ALDH1A1 (0.43) ALDH1A1GAACASP1TSHRNPSR1
SCHEMBL27650918 0.70 ALDH1A1 (0.48) ALDH1A1GAACASP1TSHRNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110819451-A Unsaturated lactones as odorants 西姆莱斯股份公司 2020-02-21 CN disclosed
CN-104703975-A Unsaturated lactones as odorants SYMRISE AG 2015-06-10 CN disclosed