Phthalic Acid

Phthalic Acid

SCHEMBL28010232

CC(C)(C)OOC(C)(C)C.O=C(O)c1ccccc1C(=O)O

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.64
ALOX15 P16050 2/20 0.64
HSD17B10 Q99714 3/20 0.53
TSHR P16473 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
AKR1C3 P42330 2/20 0.50
KDM4E B2RXH2 3/20 0.48
HPGD P15428 3/20 0.48
HMGB1 P09429 2/20 0.48
NAPRT Q6XQN6 2/20 0.48
ESR1 P03372 1/20 0.48
ITGB3 P05106 1/20 0.48
ITGA2B P08514 1/20 0.48
GGT1 P19440 1/20 0.48
PTGS1 P23219 1/20 0.48
PTGS2 P35354 1/20 0.48
BLM P54132 1/20 0.48
CA12 O43570 2/20 0.48
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Phthalic Acid SCHEMBL11341997 1.00 ALDH1A1 (0.64) ALDH1A1ALOX15HSD17B10TSHRTDP1
SCHEMBL2477857 0.86 ALDH1A1 (0.65) ALDH1A1ALOX15HSD17B10TSHRTDP1
SCHEMBL8159921 0.85 ALDH1A1 (0.45) ALDH1A1ALOX15HSD17B10TSHRTDP1
Phthalic Acid SCHEMBL1244535 0.83 ALDH1A1 (0.74) ALDH1A1ALOX15HSD17B10AKR1C3KDM4E
SCHEMBL5435699 0.83 ALDH1A1 (0.51) ALDH1A1ALOX15HSD17B10TSHRTDP1
Phthalic Acid SCHEMBL28118809 0.83 ALDH1A1 (0.82) ALDH1A1ALOX15HSD17B10TSHRTDP1
SCHEMBL153852 0.82 KDM4E (0.55) ALDH1A1ALOX15HSD17B10TSHRTDP1
Benzoic Acid SCHEMBL1299820 0.82 TSHR (0.64) ALDH1A1HSD17B10TSHRTDP1AKR1C3
Benzoic Acid SCHEMBL27295243 0.82 TSHR (0.64) ALDH1A1HSD17B10TSHRTDP1AKR1C3
Phthalic Acid SCHEMBL9744677 0.81 ALDH1A1 (0.70) ALDH1A1ALOX15HSD17B10TSHRAKR1C3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105408362-A Modified liquid diene rubber and production method for same KURARAY CO 2016-03-16 CN disclosed
CN-104540913-A Curable compositions comprising composite particles HENKEL AG & CO KGAA 2015-04-22 CN disclosed