Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | PNMT | P11086 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | TEAD2 | Q15562 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27942181 | 0.83 | PNMT (0.49) | CES1ACHEPDK2METAP1PNMT | |
| Ammonia Solution, Strong SCHEMBL28101207 | 0.80 | NOTUM (0.40) | ACHENOTUMMETAP1PNMTTEAD1 | |
| SCHEMBL27435314 | 0.76 | BCL2L1 (0.37) | CES1PDK2NOTUMMETAP1HTR2C | |
| SCHEMBL10494155 | 0.76 | CES1 (0.38) | CES1HSD11B1PTGS1PTGS2AR | |
| SCHEMBL1508269 | 0.76 | NOTUM (0.44) | CES1GAANOTUMMETAP1HTR2C | |
| SCHEMBL29634317 | 0.76 | NOTUM (0.44) | CES1GAANOTUMMETAP1HTR2C | |
| SCHEMBL18646126 | 0.75 | GALR1 (0.41) | NOTUMHSD11B1ARHTR2AHTR2C | |
| SCHEMBL28081477 | 0.75 | DRD2 (0.46) | CES1DYRK1APNMTSRD5A1SRD5A2 | |
| Dihydrophenanthrene SCHEMBL29404495 | 0.72 | CES1 (0.68) | CES1SRD5A1SRD5A2 | |
| Dihydrophenanthrene SCHEMBL155991 | 0.72 | CES1 (0.68) | CES1SRD5A1SRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104557481-B | 4,5-di-substituted phenanthrene and hydrophenanthrene liquid crystal compound and preparation method thereof | 石家庄诚志永华显示材料有限公司 | 2017-01-11 | — | — | CN | disclosed |
| CN-104557481-A | 4,5-di-substituted phenanthrene and hydrophenanthrene liquid crystal compound and preparation method thereof | SHIJIAZHUANG CHENGZHI YONGHUA DISPLAY MATERIALS CO LTD | 2015-04-29 | — | — | CN | disclosed |