Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | IDH1 | O75874 | 1/20 | 0.33 |
| ▸ | OGG1 | O15527 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11663847 | 0.78 | POLB (0.35) | ALDH1A1LMNAHPGDPOLBL3MBTL1 | |
| SCHEMBL1678464 | 0.74 | MAOA (0.45) | AKT1ALDH1A1LMNAHPGDIDH1 | |
| SCHEMBL30051272 | 0.72 | AKT1 (0.39) | AKT1ALDH1A1LMNAHPGDIDH1 | |
| SCHEMBL317112 | 0.72 | MAPT (0.57) | AKT1ALDH1A1LMNAHPGDPOLB | |
| SCHEMBL7591365 | 0.72 | POLB (0.40) | AKT1ALDH1A1LMNAHPGDIDH1 | |
| SCHEMBL1173628 | 0.71 | ATM (0.45) | ALDH1A1LMNAHPGDL3MBTL1MAPT | |
| SCHEMBL16660765 | 0.71 | PTPN1 (0.46) | ALDH1A1HPGDMAPTTDP1 | |
| SCHEMBL9702758 | 0.71 | HDAC1 (0.38) | HPGDPOLBL3MBTL1MAPTTDP1 | |
| SCHEMBL24740546 | 0.69 | DRD4 (0.40) | AKT1ALDH1A1LMNAHPGDIDH1 | |
| SCHEMBL9013220 | 0.69 | DRD4 (0.40) | AKT1ALDH1A1LMNAHPGDIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104672143-A | Method for high-selectivity synthesis of octatomic benzocyclic lactam | UNIV ZHEJIANG | 2015-06-03 | — | — | CN | disclosed |