Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | F2 | P00734 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9702759 | 0.80 | MAPT (0.41) | CYP3A4MAPTBLMTDP1PKM | |
| SCHEMBL9700915 | 0.78 | ALDH1A1 (0.38) | HDAC1TDP1PKMMEN1HPGD | |
| SCHEMBL9702052 | 0.78 | ALDH1A1 (0.46) | CYP3A4MAPTTDP1PKMPARP1 | |
| SCHEMBL16660765 | 0.77 | PTPN1 (0.46) | MAOAMAOBCYP3A4MAPTTDP1 | |
| SCHEMBL1173628 | 0.77 | ATM (0.45) | MAOAMAOBMAPTBLML3MBTL1 | |
| SCHEMBL14000035 | 0.77 | HDAC1 (0.38) | HDAC1HDAC2CYP3A4MAPTBLM | |
| SCHEMBL11663847 | 0.76 | POLB (0.35) | MAOAMAOBCYP3A4MAPTTDP1 | |
| SCHEMBL28357466 | 0.74 | HDAC1 (0.36) | HDAC1HDAC2CYP3A4MAPTBLM | |
| SCHEMBL9703287 | 0.74 | CA1 (0.46) | HDAC1HDAC2MAPTPARP1CES1 | |
| SCHEMBL9701899 | 0.73 | PARP1 (0.51) | MAPTPKMPARP1TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2180855-A | — | — | None | — | — | JP | disclosed |
| US-5120764-A | Administering penicillamine and allenylamines to inhibit crosslinking of collagen | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-06-09 | — | — | US | disclosed |
| JP-H02180855-A | LYSIL OXIDASE INHIBITOR | MERRELL DOW PHARMACEUT INC | 1990-07-13 | — | — | JP | disclosed |
| EP-0374440-A2 | Inhibitors of lysyl oxidase | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-06-27 | — | — | EP | disclosed |