Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.69 |
| ▸ | LMNA | P02545 | 7/20 | 0.69 |
| ▸ | NPC1 | O15118 | 6/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 8/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.66 |
| ▸ | HTT | P42858 | 3/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | CASP3 | P42574 | 1/20 | 0.66 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.66 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.66 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.66 |
| ▸ | AURKA | O14965 | 1/20 | 0.65 |
| ▸ | PIM1 | P11309 | 1/20 | 0.65 |
| ▸ | CDK2 | P24941 | 1/20 | 0.65 |
| ▸ | GSK3B | P49841 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30542199 | 0.85 | ALDH1A1 (0.64) | MAPTLMNANPC1KDM4EMEN1 | |
| SCHEMBL27861123 | 0.84 | KMT2A (0.68) | MAPTLMNANPC1KDM4EMEN1 | |
| SCHEMBL3191246 | 0.82 | NPC1 (1.00) | MAPTLMNANPC1KDM4EMEN1 | |
| SCHEMBL899357 | 0.81 | LMNA (0.61) | MAPTLMNANPC1KDM4EMEN1 | |
| SCHEMBL1177730 | 0.80 | MEN1 (1.00) | MAPTLMNANPC1MEN1KMT2A | |
| SCHEMBL6302157 | 0.80 | MEN1 (1.00) | MAPTLMNANPC1MEN1KMT2A | |
| SCHEMBL7261477 | 0.80 | SMN1; SMN2 (0.73) | MAPTLMNANPC1MEN1KMT2A | |
| SCHEMBL27861124 | 0.80 | SMN1; SMN2 (0.73) | MAPTLMNANPC1KDM4EMEN1 | |
| SCHEMBL4915214 | 0.80 | SMN1; SMN2 (0.73) | MAPTLMNANPC1KDM4EMEN1 | |
| SCHEMBL4600722 | 0.79 | AURKA (1.00) | MAPTLMNANPC1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650111-A | Aryl urea and aryl amide substituted oxaole pyrimindine compounds as well as preparation method and application thereof | UNIV CHINA PHARMA | 2015-05-27 | — | — | CN | disclosed |