Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.47 |
| ▸ | TBXAS1 | P24557 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NSD2 | O96028 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | PLCG1 | P19174 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.32 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.32 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.32 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | GMNN | O75496 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27549267 | 0.98 | CYP19A1 (0.46) | CYP19A1TBXAS1KDM4ETDP1KMT2A | |
| SCHEMBL12459199 | 0.77 | CYP19A1 (0.47) | CYP19A1TBXAS1KDM4ETDP1KMT2A | |
| SCHEMBL27890627 | 0.77 | CYP19A1 (0.47) | CYP19A1TBXAS1KDM4ETDP1KMT2A | |
| SCHEMBL22579802 | 0.74 | TDP1 (0.42) | CYP19A1TBXAS1KDM4ETDP1KMT2A | |
| SCHEMBL24097109 | 0.73 | CYP19A1 (0.43) | CYP19A1TBXAS1PDK2CYP1A2 | |
| SCHEMBL3860294 | 0.73 | CYP19A1 (0.43) | CYP19A1TBXAS1CYP3A4HTTALDH1A1 | |
| SCHEMBL28228601 | 0.71 | PDE5A (0.40) | CYP19A1TBXAS1KDM4ETDP1TSHR | |
| SCHEMBL28125072 | 0.71 | L3MBTL1 (0.40) | CYP19A1TBXAS1KDM4ETDP1TDP2 | |
| SCHEMBL3861319 | 0.69 | CYP3A4 (0.48) | CYP19A1TBXAS1MAPK14CYP3A4CYP1A2 | |
| SCHEMBL16550205 | 0.69 | HRH1 (0.36) | KDM4ETDP1KMT2ATDP2NSD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103221405-B | Substituted pyridine compound | DAIICHI SANKYO CO LTD | 2015-04-22 | — | — | CN | claimed |
| CN-103221405-B | Substituted pyridine compound | DAIICHI SANKYO CO LTD | 2015-04-22 | — | — | CN | disclosed |