Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 1/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3222312 | 0.89 | MAPT (0.52) | ATMMAPTSMN1; SMN2ALOX5NPC1 | |
| SCHEMBL15423692 | 0.89 | MAPT (0.49) | ATMMAPTSMN1; SMN2ALOX5NPC1 | |
| SCHEMBL3222299 | 0.89 | MAPT (0.52) | ATMMAPTSMN1; SMN2ALOX5NPC1 | |
| SCHEMBL29643038 | 0.89 | MAPT (0.52) | ATMMAPTSMN1; SMN2ALOX5NPC1 | |
| SCHEMBL20204190 | 0.88 | CYP2D6 (0.51) | ATMMAPTSMN1; SMN2ALOX5NPC1 | |
| SCHEMBL2789840 | 0.86 | PPARG (0.54) | MMEATMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2789835 | 0.86 | PPARG (0.54) | MMEATMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL2617240 | 0.86 | PPARG (0.54) | MMEATMSMN1; SMN2NPC1RAB9A | |
| SCHEMBL10521504 | 0.86 | KLK5 (0.58) | MAPTSMN1; SMN2ALOX5NPC1RAB9A | |
| SCHEMBL10519884 | 0.86 | KLK5 (0.58) | MAPTSMN1; SMN2ALOX5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102317269-B | Novel amino aza heterocyclic carboxamides | MERCK PATENT GMBH | 2015-06-17 | — | — | CN | disclosed |