Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | PPARA | Q07869 | 1/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | MME | P08473 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 3/20 | 0.43 |
| ▸ | CTSS | P25774 | 4/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2617240 | 1.00 | PPARG (0.54) | PPARGPPARAATMMMELMNA | |
| SCHEMBL2789835 | 1.00 | PPARG (0.54) | PPARGPPARAATMMMELMNA | |
| SCHEMBL2617242 | 0.89 | PPARG (0.51) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL14532784 | 0.88 | LMNA (0.63) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL6539801 | 0.88 | LMNA (0.63) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL7465229 | 0.88 | LMNA (0.63) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL30454910 | 0.87 | PPARG (0.55) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL13658641 | 0.87 | PPARG (0.53) | PPARGPPARAATMLMNAMEN1 | |
| SCHEMBL28011815 | 0.86 | MME (0.53) | PPARGPPARAATMMMEITGA4 | |
| SCHEMBL17728765 | 0.86 | PPARG (0.58) | PPARGPPARAATMMMELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486762-A | Novel compound and use method and application thereof | 中国医学科学院医药生物技术研究所 | 2024-02-02 | — | — | CN | disclosed |
| WO-2010111634-A2 | RENIN INHIBITORS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-09-30 | — | — | WO | disclosed |