⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexachloroethane SCHEMBL23458 | 0.60 | — | — | |
| Hexachloroethane SCHEMBL788209 | 0.60 | TSHR (0.50) | — | |
| Hexachloroethane SCHEMBL1330771 | 0.60 | — | — | |
| SCHEMBL3236524 | 0.59 | ALDH1A1 (0.33) | — | |
| SCHEMBL1003267 | 0.59 | — | — | |
| SCHEMBL2346731 | 0.59 | — | — | |
| SCHEMBL6842946 | 0.58 | — | — | |
| SCHEMBL129383 | 0.56 | — | — | |
| SCHEMBL5810126 | 0.56 | — | — | |
| SCHEMBL8718303 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024074685-A1 | USE OF ALBUMIN ISOFORMS PROFILES FOR THE CHARACTERIZATION OF THE ETIOLOGY AND SEVERITY OF LIVER INJURIES | Institut National de la Santé et de la Recherche Médicale (FR) | 2024-04-11 | — | — | WO | disclosed |
| US-11806379-B2 | Compositions, methods, and medical compositions for treatment of and maintaining the health of the liver | UNIGEN, INC. (US) | 2023-11-07 | — | — | US | disclosed |
| US-11331359-B2 | Compositions, methods, and medical compositions for treatment of and maintaining the health of the liver | UNIGEN, INC. (US) | 2022-05-17 | — | — | US | disclosed |
| US-20170035829-A1 | Compositions, Methods, and Medical Compositions for Treatment of and Maintaining the Health of the Liver | UNIGEN, INC. (US) | 2017-02-09 | — | — | US | disclosed |
| WO-2017011471-A1 | COMPOSITIONS, METHODS, AND MEDICAL COMPOSITIONS FOR TREATMENT OF AND MAINTAINING THE HEALTH OF THE LIVER | UNIGEN, INC. (US) | 2017-01-19 | — | — | WO | disclosed |
| WO-2017011523-A1 | COMPOSITIONS, METHODS, AND MEDICAL COMPOSITIONS FOR TREATMENT OF AND MAINTAINING THE HEALTH OF THE LIVER | UNIGEN, INC. (US) | 2017-01-19 | — | — | WO | disclosed |
| US-20170014461-A1 | Compositions, Methods, and Medical Compositions for Treatment of and Maintaining the Health of the Liver | UNIGEN, INC. (US) | 2017-01-19 | — | — | US | disclosed |
| US-20130122119-A1 | PHYLLANTHUS AMARUS COMPOSITIONS AND METHOD OF EXTRACTING SAME | NATREON, INC. (US) | 2013-05-16 | — | — | US | disclosed |
| US-20100189647-A1 | Experimental Animal As Pathological Model, Method of Producing the Experimental Animal, and Method of Using the Experimental Animal | NATIONAL UNIVERSITY CORPORATION OKAYAMA UNIVERSITY (JP) | 2010-07-29 | — | — | US | disclosed |