Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 4/20 | 0.68 |
| ▸ | NOTUM | Q6P988 | 6/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | XDH | P47989 | 2/20 | 0.48 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.48 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12923857 | 0.78 | NOTUM (0.62) | TLR8NOTUMALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL3787605 | 0.77 | TLR8 (0.72) | TLR8NOTUMALDH1A1HPGDLMNA | |
| SCHEMBL12896194 | 0.75 | NOTUM (0.47) | TLR8NOTUMALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL28012603 | 0.72 | TLR8 (0.65) | TLR8NOTUMALDH1A1HPGDLMNA | |
| SCHEMBL31417961 | 0.72 | RAB9A (0.46) | TLR8NOTUMALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL9555 | 0.71 | NOTUM (1.00) | TLR8NOTUMALDH1A1LMNAHTT | |
| Biphenyl SCHEMBL22577775 | 0.69 | NOTUM (0.95) | TLR8NOTUMALDH1A1LMNAHTT | |
| SCHEMBL4171974 | 0.69 | TSHR (0.51) | NOTUMALDH1A1HPGDLMNATSHR | |
| SCHEMBL12901577 | 0.69 | NOTUM (0.46) | NOTUMALDH1A1CHRNB2CHRNA4HPGD | |
| SCHEMBL13778386 | 0.69 | NOTUM (0.56) | NOTUMALDH1A1HPGDLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592217-B | 3 (1,3,4 oxadiazolyl) 5 phenoxypyridines analog derivative and preparation method and application | 沈阳药科大学 | 2018-03-13 | — | — | CN | disclosed |
| CN-104592217-A | 3-(1, 3, 4-oxadiazol)-5-phenoxy-pyridine derivative, preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-05-06 | — | — | CN | disclosed |
| CN-104592217-A | 3-(1, 3, 4-oxadiazol)-5-phenoxy-pyridine derivative, preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-05-06 | — | — | CN | disclosed |
| CN-104592217-A | 3-(1, 3, 4-oxadiazol)-5-phenoxy-pyridine derivative, preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-05-06 | — | — | CN | disclosed |