Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 5/20 | 0.65 |
| ▸ | LTA4H | P09960 | 3/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | NOTUM | Q6P988 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24921604 | 0.80 | NOTUM (0.50) | TLR8NOTUMALDH1A1TSHRLMNA | |
| SCHEMBL28012602 | 0.72 | TLR8 (0.68) | TLR8NOTUMALDH1A1TSHRLMNA | |
| SCHEMBL3787605 | 0.72 | TLR8 (0.72) | TLR8LTA4HCYP11B1CYP11B2NOTUM | |
| SCHEMBL6796809 | 0.70 | CA2 (0.42) | NOTUMALDH1A1TSHRHPGD | |
| SCHEMBL21241342 | 0.70 | NOTUM (0.56) | NOTUMALDH1A1TSHRLMNAHPGD | |
| SCHEMBL2644943 | 0.70 | NOTUM (0.42) | TLR8NOTUMALDH1A1HPGD | |
| SCHEMBL2746970 | 0.70 | KDM4E (0.59) | TLR8NOTUMALDH1A1LMNAHPGD | |
| SCHEMBL14355083 | 0.68 | CYP11B1 (0.73) | LTA4HCYP11B1CYP11B2NOTUMTSHR | |
| SCHEMBL3405254 | 0.67 | TLR8 (0.46) | TLR8NOTUMALDH1A1TSHRLMNA | |
| SCHEMBL16418303 | 0.66 | LTA4H (0.57) | LTA4HCYP11B1CYP11B2ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104592217-A | 3-(1, 3, 4-oxadiazol)-5-phenoxy-pyridine derivative, preparation method and application thereof | UNIV SHENYANG PHARMACEUTICAL | 2015-05-06 | — | — | CN | disclosed |