SCHEMBL28013286

SCHEMBL28013286

COc1ccc(SCC2(C=O)CCCCC2)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
APP P05067 1/20 0.41
RYR2 Q92736 2/20 0.40
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
SLC6A4 P31645 2/20 0.37
SLC6A3 Q01959 2/20 0.37
GRIN1 Q05586 1/20 0.37
GRIN2A Q12879 1/20 0.37
GRIN2B Q13224 1/20 0.37
DAO P14920 1/20 0.36
ALDH1A1 P00352 4/20 0.36
CYP2A6 P11509 1/20 0.36
PTGIR P43119 1/20 0.35
MAOA P21397 1/20 0.35
MAOB P27338 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
MAPK1 P28482 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15944449 0.74 ALDH1A1 (0.40) ALDH1A1GAAMAPK1HPGD
SCHEMBL1951997 0.69 MTNR1A (0.47) APPMTNR1AMTNR1BDAOALDH1A1
SCHEMBL21964255 0.68 SLC6A4 (0.50) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL21961572 0.68 SLC6A4 (0.50) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL11619962 0.67 SLC6A4 (0.45) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL21964328 0.66 SLC6A4 (0.47) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B
SCHEMBL11287405 0.66 MTNR1A (0.53) APPRYR2MTNR1AMTNR1BDAO
SCHEMBL23329862 0.66 MTNR1A (0.46) RYR2MTNR1AMTNR1BALDH1A1KDM4E
SCHEMBL418525 0.65 ALDH1A1 (0.59) APPRYR2MTNR1AMTNR1BDAO
SCHEMBL6792552 0.64 SLC6A4 (0.49) SLC6A4SLC6A3GRIN1GRIN2AGRIN2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104496870-A Catalytic synthesis method of sulfur-containing carboxylic acid compound and sulfur-containing amide compound UNIV HUNAN 2015-04-08 CN disclosed