Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28013754 | 1.00 | NR1H2 (0.41) | NR1H2EPHX2ALDH1A1ATM | |
| SCHEMBL27979075 | 0.90 | NR1H2 (0.40) | NR1H2EPHX2 | |
| SCHEMBL27993435 | 0.87 | NR1H2 (0.35) | NR1H2 | |
| SCHEMBL28031806 | 0.86 | ATM (0.30) | ATM | |
| SCHEMBL27593149 | 0.86 | NR1H2 (0.38) | NR1H2ATM | |
| SCHEMBL27593151 | 0.86 | NR1H2 (0.38) | NR1H2ATM | |
| SCHEMBL28794950 | 0.86 | NR1H2 (0.38) | NR1H2ATM | |
| SCHEMBL25435857 | 0.84 | ATM (0.31) | ATM | |
| SCHEMBL28803663 | 0.84 | CHRM2 (0.35) | ATM | |
| SCHEMBL28181637 | 0.84 | CHRM2 (0.35) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102741240-B | Pyrimidine compounds as delta opioid receptor modulators | JANSSEN PHARMACEUTICA NV | 2015-05-06 | — | — | CN | disclosed |