Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27979075 | 0.94 | NR1H2 (0.40) | NR1H2 | |
| SCHEMBL28013754 | 0.87 | NR1H2 (0.41) | NR1H2 | |
| SCHEMBL28013755 | 0.87 | NR1H2 (0.41) | NR1H2 | |
| SCHEMBL27766894 | 0.87 | ALOX5 (0.37) | ALOX5 | |
| SCHEMBL27879012 | 0.84 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL27879002 | 0.84 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL28013168 | 0.84 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL29851808 | 0.84 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL27905596 | 0.84 | ALOX5 (0.32) | ALOX5 | |
| SCHEMBL28794950 | 0.83 | NR1H2 (0.38) | NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102232076-B | Pyrrolopyrazinyl urea kinase inhibitors | HOFFMANN LA ROCHE | 2014-12-31 | — | — | CN | disclosed |