Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CTSD | P07339 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27448977 | 0.77 | MAPT (0.55) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL8414412 | 0.76 | PTGDR2 (0.57) | PTGDR2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL28910346 | 0.76 | PTPN11 (0.42) | MEN1KMT2AMAPTCYP2C9 | |
| SCHEMBL7431459 | 0.73 | HPGD (0.39) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL6572279 | 0.73 | BCL9 (0.43) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL29388652 | 0.73 | PTGDR2 (0.68) | PTGDR2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL867129 | 0.73 | PTGDR2 (0.68) | PTGDR2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL11541420 | 0.72 | CYP2C9 (0.65) | PTGDR2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL5898858 | 0.72 | MAPT (0.67) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL7434951 | 0.72 | LMNA (0.51) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104491864-A | Controlled Release Antimicrobial Compositions And Methods For The Treatment Of Otic Disorders | OTONOMY INC | 2015-04-08 | — | — | CN | disclosed |