Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7429291 | 0.84 | BCL9 (0.41) | BCL9CTNNB1KMT2AKDM4EMEN1 | |
| SCHEMBL7429793 | 0.83 | ABCB1 (0.42) | BCL9CTNNB1KMT2AMEN1MAPT | |
| SCHEMBL7431099 | 0.81 | BCL9 (0.39) | BCL9CTNNB1KMT2AKDM4EMEN1 | |
| SCHEMBL7431459 | 0.81 | HPGD (0.39) | KMT2AKDM4EMEN1MAPTMAPK1 | |
| SCHEMBL7429307 | 0.80 | BCL9 (0.41) | BCL9CTNNB1KMT2AKDM4EMEN1 | |
| SCHEMBL27762116 | 0.77 | KMT2A (0.52) | KMT2AKDM4EMEN1RECQLMAPT | |
| SCHEMBL27448977 | 0.76 | MAPT (0.55) | KMT2AKDM4EMEN1RECQLMAPT | |
| SCHEMBL28942485 | 0.76 | MAPT (0.62) | KMT2AKDM4EMEN1RECQLMAPT | |
| SCHEMBL28014140 | 0.73 | PTGDR2 (0.52) | KMT2AKDM4EMEN1MAPTMAPK1 | |
| SCHEMBL28910346 | 0.72 | PTPN11 (0.42) | KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020037931-A1 | Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them | PORTELA & C.A., S.A. (PT) | 2002-03-28 | — | — | US | claimed |
| EP-1167341-A1 | Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them | Portela & Ca., S.A. (PT) | 2002-01-02 | — | — | EP | claimed |
| WO-2001098250-A1 | SUBSTITUTED NITRATED CATECHOLS, THEIR USE IN THE TREATMENT OF SOME CENTRAL AND PERIPHERAL NERVOUS SYSTEM DISORDERS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PORTELA & CA SA (PT) | 2001-12-27 | — | — | WO | claimed |
| US-20040192961-A1 | Method for the nitration of phenolic compounds | PORTELA, C.A., S.A. (PT) | 2004-09-30 | — | — | US | disclosed |
| EP-1409446-A1 | METHOD FOR THE NITRATION OF PHENOLIC COMPOUNDS | Portela & CA SA (PT) | 2004-04-21 | — | — | EP | disclosed |
| WO-2003011810-A1 | METHOD FOR THE NITRATION OF PHENOLIC COMPOUNDS | PORTELA & CA SA (PT) | 2003-02-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020037931-A1 | Substituted nitrated catechols, their use in the treatment of some central and peripheral nervous system disorders and pharmaceutical compositions containing them | SLC6A2, COMT, SLC6A3 | BCL9 4557/4885CTNNB1 3047/4885KMT2A 2898/4885 |
| US-20040192961-A1 | Method for the nitration of phenolic compounds | NOS1, NOS2, NOS3 | BCL9 2879/4885CTNNB1 4006/4885KMT2A 2933/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.