Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.58 |
| ▸ | HTR2B | P41595 | 4/20 | 0.58 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.42 |
| ▸ | PYGL | P06737 | 1/20 | 0.41 |
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3112268 | 0.79 | PYGL (0.49) | HTR2CCA12CA1CA2CA9 | |
| SCHEMBL29622425 | 0.79 | PYGL (0.49) | HTR2CCA12CA1CA2CA9 | |
| SCHEMBL28305388 | 0.78 | CA1 (0.77) | CA12CA1CA2CA9GFER | |
| SCHEMBL2404788 | 0.78 | CA12 (0.54) | HTR2CHTR2BCA12CA1CA2 | |
| SCHEMBL10893085 | 0.78 | CA12 (0.54) | HTR2CHTR2BCA12CA1CA2 | |
| SCHEMBL17785623 | 0.78 | GFER (0.56) | CA12CA1CA2CA9GFER | |
| SCHEMBL1439875 | 0.78 | CA12 (0.54) | CA12CA1CA2CA9GFER | |
| Hydrochloric Acid SCHEMBL30142485 | 0.77 | PYGL (0.48) | HTR2CCA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL2144161 | 0.77 | PYGL (0.48) | HTR2CCA12CA1CA2CA9 | |
| Methane SCHEMBL8122180 | 0.77 | CA12 (0.53) | HTR2CHTR2BCA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102883607-B | Compounds for the treatment of cancer | GTX INC | 2015-07-22 | — | — | CN | disclosed |
| CN-104592205-A | COMPOUNDS FOR TREATMENT OF CANCER | GTX INC | 2015-05-06 | — | — | CN | disclosed |