Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.54 |
| ▸ | CA2 | P00918 | 4/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.42 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1439878 | 0.98 | CA12 (0.53) | CA12CA1CA2CA9GFER | |
| Methane SCHEMBL8122180 | 0.98 | CA12 (0.53) | CA12CA1CA2CA9GFER | |
| SCHEMBL1806454 | 0.90 | GFER (0.59) | CA12CA1CA2CA9GFER | |
| SCHEMBL9236433 | 0.87 | CA12 (0.71) | CA12CA1CA2CA9GFER | |
| SCHEMBL17785623 | 0.83 | GFER (0.56) | CA12CA1CA2CA9GFER | |
| SCHEMBL28305388 | 0.83 | CA1 (0.77) | CA12CA1CA2CA9GFER | |
| SCHEMBL1439875 | 0.83 | CA12 (0.54) | CA12CA1CA2CA9GFER | |
| SCHEMBL2404788 | 0.83 | CA12 (0.54) | CA12CA1CA2CA9GFER | |
| SCHEMBL28014273 | 0.78 | HTR2C (0.58) | CA12CA1CA2CA9GFER | |
| Sulfuric Acid SCHEMBL28330425 | 0.77 | ADRA2A (0.46) | CA12CA1CA2CA9GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8309059-B2 | Reactive cyanine compounds | PROMEGA CORPORATION (US) | 2012-11-13 | — | — | US | disclosed |
| US-20110053162-A1 | REACTIVE CYANINE COMPOUNDS | PROMEGA CORPORATION (US) | 2011-03-03 | — | — | US | disclosed |
| US-4622400-A | SULFONATION, ALKALI FUSION | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) | 1986-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110053162-A1 | REACTIVE CYANINE COMPOUNDS | IK, CRYAA, POLL | CA12 225/4885CA1 599/4885CA2 606/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.