Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SSTR4 | P31391 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F13A1 | P00488 | 1/20 | 0.46 |
| ▸ | ESR1 | P03372 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | ESRRG | P62508 | 3/20 | 0.44 |
| ▸ | ESRRB | O95718 | 2/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28411736 | 0.85 | SSTR4 (0.46) | SSTR4MEN1KMT2ANPC1RAB9A | |
| SCHEMBL27924427 | 0.85 | SSTR4 (0.46) | SSTR4KDM4ETSHRNPC1RAB9A | |
| SCHEMBL7248839 | 0.83 | POLB (0.56) | SSTR4ESR1ESRRGESRRBESR2 | |
| SCHEMBL4171208 | 0.82 | ESR1 (0.59) | KDM4EESR1BLMESR2MEN1 | |
| SCHEMBL28906548 | 0.82 | LPL (0.47) | SSTR4CA2 | |
| SCHEMBL4297210 | 0.82 | KDM4E (0.42) | KDM4EF13A1ESR1BLMESRRG | |
| SCHEMBL4297214 | 0.82 | KDM4E (0.42) | KDM4EF13A1ESR1BLMESRRG | |
| SCHEMBL28134378 | 0.81 | FFAR1 (0.56) | KDM4EMEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL5969031 | 0.80 | ST14 (0.50) | SSTR4 | |
| SCHEMBL11138866 | 0.78 | ADRB1 (0.44) | SSTR4BLMMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104961672-B | A kind of synthetic method of the tartrate of N (4 luorobenzyl) N (base of 1 methyl piperidine 4) N ' (4 isobutoxy benzyl) urea | 沈阳药科大学 | 2017-10-20 | — | — | CN | disclosed |
| CN-104961672-A | Synthetic method of tartrate of N-(4-fluorobenzyl)-N-(1-methylpiperidine-4-yl)-N'-(4-isobutoxybenzyl)urea | UNIV SHENYANG PHARMACEUTICAL | 2015-10-07 | — | — | CN | disclosed |