SCHEMBL28014378

SCHEMBL28014378

C=CC(=O)C(O)COC(=O)CCC(=O)O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.36
MAPT P10636 2/20 0.36
KDM2A Q9Y2K7 3/20 0.34
EGLN1 Q9GZT9 2/20 0.34
KDM6B O15054 1/20 0.34
KDM5C P41229 1/20 0.34
PHF8 Q9UPP1 1/20 0.34
TET2 Q6N021 3/20 0.33
TSHR P16473 2/20 0.33
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
TET3 O43151 1/20 0.33
SLC6A2 P23975 1/20 0.33
SLC6A4 P31645 1/20 0.33
BLM P54132 1/20 0.33
SLC6A3 Q01959 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
SUCNR1 Q9BXA5 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28150222 0.98 LMNA (0.35) LMNAMAPTKDM2AEGLN1KDM6B
SCHEMBL5066937 0.92 MAPT (0.40) LMNAMAPTTSHRMEN1KMT2A
SCHEMBL28108444 0.85 MAPT (0.50) LMNAMAPTTSHRMEN1KMT2A
SCHEMBL27994589 0.84 TSHR (0.46) LMNAMAPTTSHRMEN1KMT2A
SCHEMBL28080699 0.82 TSHR (0.45) LMNAMAPTTSHRMEN1KMT2A
SCHEMBL28017251 0.82 TSHR (0.45) LMNAMAPTTSHRMEN1KMT2A
SCHEMBL8421166 0.81 LMNA (0.33) LMNAMAPTKDM2AEGLN1KDM6B
SCHEMBL28073049 0.79 KDM2A (0.36) LMNAMAPTKDM2AEGLN1KDM6B
SCHEMBL28356995 0.77 TSHR (0.38) LMNAMAPTKDM2AEGLN1KDM6B
SCHEMBL1134609 0.76 MAPT (0.58) LMNAMAPTKDM2AEGLN1KDM6B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109627658-A Composition comprising the pure and mild Nano capsule containing liquid crystal media of functional polyethylene 默克专利股份有限公司 2019-04-16 CN disclosed
CN-106414071-B Stacked film 日立化成株式会社 2018-07-13 CN disclosed
CN-104936774-B Layered product, conductive pattern, the manufacture method of circuit and layered product DIC株式会社 2017-11-14 CN disclosed
CN-104221481-B Conductive pattern, circuit, the manufacture method of electromagnetic wave shielding thing and conductive pattern DIC株式会社 2017-08-22 CN disclosed
CN-104619652-B Biocatalyst composition and the method for using 微视生物技术有限公司 2017-06-13 CN disclosed
CN-106414071-A Laminate film 日立化成株式会社 2017-02-15 CN disclosed
CN-104619652-A Novel biocatalyst compositions and processes for use MICROVI BIOTECH INC 2015-05-13 CN disclosed