SCHEMBL28356995

SCHEMBL28356995

C=CC(=O)OC(O)COC(=O)CCC(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 8/20 0.38
LMNA P02545 2/20 0.33
MAPT P10636 1/20 0.33
ALDH1A1 P00352 5/20 0.32
TP53 P04637 3/20 0.32
HIF1A Q16665 3/20 0.32
CYP3A4 P08684 3/20 0.32
HSD17B10 Q99714 1/20 0.32
EGLN1 Q9GZT9 2/20 0.32
KDM6B O15054 1/20 0.32
KDM5C P41229 1/20 0.32
PHF8 Q9UPP1 1/20 0.32
KDM2A Q9Y2K7 1/20 0.32
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
BLM P54132 1/20 0.31
SLC6A3 Q01959 1/20 0.31
MEN1 O00255 1/20 0.31
CYP2D6 P10635 1/20 0.31
NFKB1 P19838 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17097350 0.93 TSHR (0.42) TSHRLMNAMAPTALDH1A1TP53
SCHEMBL7165107 0.85 TSHR (0.39) TSHRLMNAMAPTALDH1A1TP53
SCHEMBL19845084 0.82 TSHR (0.49) TSHRLMNAMAPTALDH1A1TP53
SCHEMBL19845081 0.82 TSHR (0.49) TSHRLMNAMAPTALDH1A1TP53
SCHEMBL1071857 0.82 TSHR (0.49) TSHRLMNAMAPTALDH1A1TP53
SCHEMBL27993897 0.81 TSHR (0.47) TSHRLMNAMAPTALDH1A1TP53
SCHEMBL4431912 0.80 TSHR (0.57) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL3135233 0.80 ALDH1A1 (0.40) TSHRLMNAMAPTALDH1A1HPGD
Succinic Acid SCHEMBL28408595 0.79 TSHR (0.36) TSHRLMNAMAPTALDH1A1TP53
Succinic Acid SCHEMBL27825761 0.77 TSHR (0.37) TSHRLMNAMAPTALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114806068-B High-strength high-rigidity environment-friendly weather-resistant ABS resin and preparation method thereof 万华化学(四川)有限公司 2024-02-27 CN claimed
CN-113801429-B Impact-resistant heat-resistant flame-retardant ABS resin and preparation method thereof 万华化学(四川)有限公司 2024-02-02 CN claimed
CN-108484849-B Ionic polymer antistatic agent and preparation method thereof 中红普林医疗用品股份有限公司 2021-11-16 CN claimed
CN-108504163-B Bioengineering interior wall putty powder and preparation method thereof 漳州市龙文区康保建材有限公司 2020-02-11 CN claimed
CN-113801429-B Impact-resistant heat-resistant flame-retardant ABS resin and preparation method thereof 万华化学(四川)有限公司 2024-02-02 CN disclosed
CN-116333207-A Light-responsive polymer, preparation method thereof and reversible adjustment method of surface roughness 浙江清华柔性电子技术研究院 2023-06-27 CN disclosed
CN-116330826-A Controllable transfer printing equipment and controllable transfer printing method 浙江清华柔性电子技术研究院 2023-06-27 CN disclosed
CN-115210271-A N-substituted maleimide polymer and process for producing the same 株式会社日本触媒 2022-10-18 CN disclosed
CN-108484849-B Ionic polymer antistatic agent and preparation method thereof 中红普林医疗用品股份有限公司 2021-11-16 CN disclosed
CN-108504163-B Bioengineering interior wall putty powder and preparation method thereof 漳州市龙文区康保建材有限公司 2020-02-11 CN disclosed