Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1B | P28222 | 5/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | FABP1 | P07148 | 1/20 | 0.44 |
| ▸ | OGG1 | O15527 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL275479 | 0.90 | SLC22A6 (0.51) | HTR1BTSHRNR2E1ALDH1A1KDM4E | |
| Ether SCHEMBL1995908 | 0.89 | TSHR (0.48) | HTR1BTSHRALDH1A1KDM4EHPGD | |
| Ammonia Solution, Strong SCHEMBL10605012 | 0.88 | FABP1 (0.50) | HTR1BTSHRNR2E1ALDH1A1KDM4E | |
| Water SCHEMBL2147729 | 0.88 | FABP1 (0.50) | HTR1BTSHRNR2E1ALDH1A1KDM4E | |
| Amphetamine SCHEMBL27801601 | 0.81 | SLC6A2 (0.49) | ALDH1A1KDM4EHPGDTDP1FABP1 | |
| SCHEMBL4484229 | 0.80 | TSHR (0.46) | HTR1BTSHRALDH1A1KDM4EHPGD | |
| SCHEMBL10647420 | 0.78 | SLC22A6 (0.53) | ALDH1A1KDM4EHPGDTDP1FABP1 | |
| Ethylenediamine SCHEMBL27862580 | 0.78 | HTR1B (0.61) | HTR1BNR2E1ALDH1A1KDM4EHPGD | |
| Sulfuric Acid SCHEMBL28146196 | 0.77 | ALDH1A1 (0.46) | HTR1BTSHRALDH1A1KDM4EHPGD | |
| SCHEMBL21569210 | 0.76 | ALDH1A1 (0.46) | HTR1BTSHRALDH1A1KDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104610069-A | Preparation method of high purity cinacalcet hydrochloride | CHANGZHOU SUNLIGHT PHARM CO LTD | 2015-05-13 | — | — | CN | disclosed |