SCHEMBL28014691

SCHEMBL28014691

NC(=O)c1cccc(CC2CC2)c1N

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
JAK1 P23458 1/20 0.38
JAK3 P52333 1/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 2/20 0.38
GAA P10253 1/20 0.38
PARP2 Q9UGN5 1/20 0.37
AURKA O14965 1/20 0.37
RPS6KB1 P23443 1/20 0.37
PARP1 P09874 4/20 0.36
OPRM1 P35372 1/20 0.36
OPRD1 P41143 1/20 0.36
OPRK1 P41145 1/20 0.36
ABCB11 O95342 1/20 0.36
LMNA P02545 1/20 0.36
PTGS1 P23219 1/20 0.36
ADORA1 P30542 1/20 0.36
PTGS2 P35354 1/20 0.36
TP53 P04637 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2468475 0.87 G6PD (0.49) ALDH1A1ABCB11LMNAPTGS1ADORA1
SCHEMBL2303340 0.84 KDM4E (0.44) MEN1KMT2AJAK1JAK3KDM4E
SCHEMBL28871905 0.83 MEN1 (0.39) MEN1KMT2AJAK1JAK3KDM4E
SCHEMBL28871903 0.81 GRIK1 (0.40) MEN1KMT2AJAK1JAK3KDM4E
SCHEMBL28871862 0.79 KDM4E (0.41) KDM4EALDH1A1GAAPARP2AURKA
SCHEMBL8943463 0.78 ABCB11 (0.45) MEN1KMT2AKDM4EALDH1A1GAA
SCHEMBL9996739 0.78 TP53 (0.47) MEN1KMT2AKDM4EALDH1A1TP53
SCHEMBL29818185 0.78 TP53 (0.43) MEN1KMT2AKDM4EALDH1A1GAA
SCHEMBL5545298 0.77 PARP1 (0.46) MEN1KMT2AKDM4EALDH1A1GAA
SCHEMBL3622854 0.77 PARP1 (0.47) MEN1KMT2AKDM4EALDH1A1PARP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104496901-B The manufacture method of anthranilamide compound ISHIHARA SANGYO KAISHA, LTD. (JP) 2016-05-25 CN disclosed
CN-104496901-A Process for production of anthranilamide compound ISHIHARA SANGYO KAISHA 2015-04-08 CN disclosed