Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 11/20 | 0.36 |
| ▸ | JAK3 | P52333 | 11/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.36 |
| ▸ | PKN2 | Q16513 | 3/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.36 |
| ▸ | LCK | P06239 | 2/20 | 0.36 |
| ▸ | RET | P07949 | 2/20 | 0.36 |
| ▸ | KDR | P35968 | 2/20 | 0.36 |
| ▸ | CAMK1D | Q8IU85 | 2/20 | 0.36 |
| ▸ | PRKACA | P17612 | 1/20 | 0.36 |
| ▸ | LTK | P29376 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | PRKX | P51817 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28025455 | 0.84 | DPP4 (0.39) | DPP4PIK3CDSMN1; SMN2LMNA | |
| SCHEMBL27955404 | 0.79 | SMN1; SMN2 (0.39) | DPP4ALDH1A1MAPTPIK3CDSMN1; SMN2 | |
| SCHEMBL23895694 | 0.78 | JAK3 (0.41) | MEN1ALDH1A1MAPTKMT2AJAK2 | |
| SCHEMBL17308196 | 0.78 | JAK3 (0.41) | MEN1ALDH1A1MAPTKMT2AJAK2 | |
| SCHEMBL30497351 | 0.78 | JAK3 (0.41) | MEN1ALDH1A1MAPTKMT2AJAK2 | |
| SCHEMBL22388263 | 0.75 | JAK3 (0.39) | MEN1ALDH1A1MAPTKMT2AJAK2 | |
| SCHEMBL27756928 | 0.75 | ALDH1A1 (0.51) | DPP4MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL29143876 | 0.75 | EPHX2 (0.43) | DPP4MEN1ALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL17320497 | 0.75 | PIK3CD (0.41) | DPP4MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL17306173 | 0.74 | IRAK4 (0.39) | MEN1ALDH1A1MAPTKMT2AJAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104650092-B | Substituted heteroaryl compound and combinations thereof and purposes | 广东东阳光药业有限公司 | 2017-11-10 | — | — | CN | disclosed |
| CN-104650092-A | Substituted ceteroary compound as well as composition and application thereof | GUANGDONG HEC PHARMACEUTICAL | 2015-05-27 | — | — | CN | disclosed |