Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 13/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143876 | 0.91 | EPHX2 (0.43) | DPP4SMN1; SMN2EPHX2LMNA | |
| SCHEMBL28014875 | 0.84 | DPP4 (0.43) | DPP4SMN1; SMN2PIK3CDLMNA | |
| SCHEMBL27955404 | 0.80 | SMN1; SMN2 (0.39) | DPP4SMN1; SMN2PIK3CDEPHX2LMNA | |
| SCHEMBL27756928 | 0.80 | ALDH1A1 (0.51) | DPP4SMN1; SMN2LMNA | |
| SCHEMBL27962873 | 0.79 | CHRM3 (0.41) | DPP4SMN1; SMN2 | |
| SCHEMBL25450487 | 0.77 | PIK3CD (0.42) | PIK3CDEPHX2PIK3R1 | |
| SCHEMBL25247324 | 0.77 | CHRM3 (0.46) | DPP4SMN1; SMN2LMNA | |
| SCHEMBL27704474 | 0.77 | DPP4 (0.39) | DPP4SMN1; SMN2LMNA | |
| SCHEMBL28882149 | 0.77 | CA2 (0.38) | DPP4SMN1; SMN2LMNA | |
| SCHEMBL28830382 | 0.76 | DPP4 (0.37) | DPP4SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104918940-A | Purine inhibitors of human phosphatidylinositol 3-kinase | MERCK SHARP & DOHME | 2015-09-16 | — | — | CN | disclosed |