Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PGK1 | P00558 | 8/20 | 0.37 |
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28296447 | 0.82 | ALDH1A1 (0.34) | HPGDHSD17B10KDM4EALDH1A1MAPT | |
| SCHEMBL28176316 | 0.80 | GAA (0.49) | PDE4BPDE4DHSD17B10CHRM2ALDH1A1 | |
| SCHEMBL1355824 | 0.79 | APP (0.40) | HPGDALDH1A1LMNAGAAMAPT | |
| SCHEMBL8441061 | 0.78 | CYP3A4 (0.35) | HPGDKDM4EALDH1A1TSHRGAA | |
| SCHEMBL7474104 | 0.76 | CYP3A4 (0.47) | HPGDKDM4EALDH1A1TSHRGAA | |
| SCHEMBL6315248 | 0.76 | TDP1 (0.48) | HPGDHSD17B10KDM4EALDH1A1TSHR | |
| SCHEMBL1355211 | 0.76 | KMT2A (0.52) | BRD4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL2899236 | 0.75 | HTT (0.55) | KDM4EALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL29001789 | 0.73 | KMT2A (0.30) | L3MBTL1 | |
| SCHEMBL16719713 | 0.73 | HTT (0.38) | HSD17B10ALDH1A1TSHRLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |
| CN-1705670-A | 2, 3-dihydro-6-nitroimidazo [2, 1-b ] oxazole compounds | OTSUKA PHARMA CO LTD (JP) | 2005-12-07 | — | — | CN | disclosed |