Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900768 | 0.88 | LMNA (0.49) | HTTMAPK1GAAALDH1A1POLB | |
| SCHEMBL2902630 | 0.86 | KMT2A (0.58) | SMN1; SMN2KMT2AMEN1GAAALDH1A1 | |
| SCHEMBL3002053 | 0.84 | ALDH1A1 (0.51) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL1355596 | 0.82 | ALDH1A1 (0.45) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL1355211 | 0.82 | KMT2A (0.52) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL3001126 | 0.81 | MEN1 (0.60) | SMN1; SMN2MAPTKMT2AMEN1GAA | |
| SCHEMBL2900696 | 0.80 | ALDH1A1 (0.47) | HTTSMN1; SMN2MAPTKMT2AMEN1 | |
| SCHEMBL2897540 | 0.80 | KDM4E (0.50) | HTTSMN1; SMN2MAPTMAPK1KMT2A | |
| SCHEMBL2900503 | 0.79 | KDM4E (0.48) | MAPTKMT2AMEN1GAAALDH1A1 | |
| SCHEMBL1355851 | 0.79 | SMN1; SMN2 (0.56) | SMN1; SMN2MAPTKMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101367749-B | A set of mesidino mesitoyl derivant, preparation and application thereof | INST MEDICINAL BIOTECHNOLOGY | 2013-04-24 | — | — | CN | disclosed |
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
| CN-101367749-A | A set of mesidino mesitoyl derivant, preparation and application thereof | MEDICINE AND BIOENGINEERING IN (CN) | 2009-02-18 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | HTT 2101/4885SMN1; SMN2 2519/4885MAPT 3480/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.