Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5547422 | 0.74 | LMNA (0.42) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL3090718 | 0.74 | CA1 (0.43) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL4525438 | 0.74 | TSHR (0.43) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL183037 | 0.74 | ALDH1A1 (0.56) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL7671015 | 0.74 | LMNA (0.42) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL28379067 | 0.73 | MAPT (0.40) | LMNACYP2A6NPC1CA1CA2 | |
| SCHEMBL997643 | 0.72 | — | — | |
| SCHEMBL27978234 | 0.70 | HSD17B10 (0.42) | LMNACYP2A6NPC1CA1CA2 | |
| 1,4-Dichlorobenzene SCHEMBL27569172 | 0.69 | LMNA (0.73) | LMNACYP2A6CA1CA2ALDH1A1 | |
| SCHEMBL2438585 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |