SCHEMBL28015148

SCHEMBL28015148

NC(CCc1cc[c]cc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 2/20 0.40
ERAP1 Q9NZ08 2/20 0.40
ERAP2 Q6P179 1/20 0.40
SCN4A P35499 2/20 0.39
ACP3 P15309 1/20 0.39
KCNH2 Q12809 1/20 0.37
DPP4 P27487 2/20 0.37
F2 P00734 1/20 0.37
HRH1 P35367 1/20 0.36
GRIN2D O15399 1/20 0.36
GRIN3B O60391 1/20 0.36
GRIN1 Q05586 1/20 0.36
GRIN2A Q12879 1/20 0.36
GRIN2B Q13224 1/20 0.36
GRIN2C Q14957 1/20 0.36
GRIN3A Q8TCU5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8067078 0.86 ANPEP (0.50) ANPEPERAP1ERAP2SCN4AACP3
SCHEMBL5924988 0.86 ANPEP (0.50) ANPEPERAP1ERAP2SCN4AACP3
SCHEMBL855071 0.86 ANPEP (0.50) ANPEPERAP1ERAP2SCN4AACP3
Hydrochloric Acid SCHEMBL9635016 0.84 ANPEP (0.48) ANPEPERAP1ERAP2SCN4AACP3
SCHEMBL8473980 0.82 KCNH2 (0.48) ACP3KCNH2HRH1
SCHEMBL6432692 0.82 ANPEP (0.50) ANPEPERAP1ERAP2ACP3KCNH2
SCHEMBL27629334 0.81 GRIN2D (0.46) ANPEPSCN4ADPP4GRIN2DGRIN3B
SCHEMBL28361302 0.78 RIPK1 (0.47) ACP3KCNH2
SCHEMBL8169961 0.77 TACR1 (0.40) SCN4A
SCHEMBL20725551 0.77 ANPEP (0.46) ANPEPERAP1ERAP2ACP3KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108699262-A Resin sheet and resin sheet solidfied material 日立化成株式会社 2018-10-23 CN disclosed
CN-102532162-B 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles OTSUKA PHARMA CO LTD 2015-05-27 CN disclosed