Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 2/20 | 0.36 |
| ▸ | TPSD1 | Q9BZJ3 | 2/20 | 0.36 |
| ▸ | TPSG1 | Q9NRR2 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1490076 | 0.92 | GABRA1 (0.41) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL7344765 | 0.90 | GABRA1 (0.39) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL306364 | 0.90 | GABRA1 (0.39) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL14127554 | 0.84 | CHRM2 (0.36) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL21003949 | 0.84 | SLC6A1 (0.44) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL1489698 | 0.84 | SLC6A1 (0.44) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL14127544 | 0.84 | CHRM2 (0.36) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| SCHEMBL14127659 | 0.84 | CHRM2 (0.36) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL27675051 | 0.82 | SLC6A1 (0.42) | CHRM3CHRM2CHRM4CHRM1CHRM5 | |
| Hydrochloric Acid SCHEMBL27584414 | 0.82 | SLC6A1 (0.42) | CHRM3CHRM2CHRM4CHRM1CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104619709-A | Imidazopyridine derivatives as modulators of TNF activity | UCB PHARMA SA | 2015-05-13 | — | — | CN | disclosed |