Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | MPL | P40238 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015074 | 0.78 | ALDH1A1 (0.37) | ALDH1A1HSD17B10KDM4E | |
| SCHEMBL28015666 | 0.74 | ALDH1A1 (0.37) | ALDH1A1KDM4ENPC1RAB9A | |
| SCHEMBL744132 | 0.69 | SMN1; SMN2 (0.46) | MAPK14ALDH1A1HSD17B10KDM4ENPC1 | |
| SCHEMBL25511509 | 0.69 | MPL (0.46) | MAPK14MPLALDH1A1GSTO1NPC1 | |
| SCHEMBL30166481 | 0.69 | MPL (0.46) | MAPK14MPLALDH1A1GSTO1NPC1 | |
| Benzene SCHEMBL27538848 | 0.68 | SMN1; SMN2 (0.44) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL2092932 | 0.67 | MPL (0.40) | MAPK14MPLALDH1A1KDM4EGSTO1 | |
| SCHEMBL2095688 | 0.67 | MAPK14 (0.42) | MAPK14MPLALDH1A1HSD17B10KDM4E | |
| Hydrazine SCHEMBL27575629 | 0.66 | SMN1; SMN2 (0.47) | ALDH1A1HSD17B10KDM4ENPC1RAB9A | |
| SCHEMBL30713695 | 0.66 | ALDH1A1 (0.37) | ALDH1A1HSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |