Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | F2RL3 | Q96RI0 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | GCGR | P47871 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
| ▸ | MBNL1 | Q9NR56 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28015656 | 0.83 | RAB9A (0.36) | ALDH1A1MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL28015742 | 0.81 | ALDH1A1 (0.38) | ALDH1A1MAPTMAPK1KDM4ERAB9A | |
| SCHEMBL28015705 | 0.75 | KDM4E (0.38) | ALDH1A1MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL28015191 | 0.74 | MAPK14 (0.37) | ALDH1A1KDM4ERAB9ANPC1 | |
| SCHEMBL28015149 | 0.71 | NPC1 (0.46) | ALDH1A1MAPTMAPK1RAB9ANPC1 | |
| SCHEMBL2623678 | 0.71 | SMN1; SMN2 (0.61) | ALDH1A1MAPTMAPK1KDM4ERAB9A | |
| SCHEMBL28015158 | 0.71 | HSD11B1 (0.38) | MAPTKDM4ERAB9ANPC1POLB | |
| SCHEMBL28015180 | 0.70 | KDM4E (0.41) | ALDH1A1MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL2096848 | 0.69 | HCRTR1 (0.40) | ALDH1A1KDM4ERAB9ANPC1PKM | |
| SCHEMBL2095462 | 0.69 | MBNL1 (0.45) | ALDH1A1MAPTKDM4ERAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102532162-B | 2,3-dihydro-6-nitroimidazo[2,1-b]oxazoles | OTSUKA PHARMA CO LTD | 2015-05-27 | — | — | CN | disclosed |