Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 9/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.33 |
| ▸ | PDCD1 | Q15116 | 3/20 | 0.33 |
| ▸ | CD274 | Q9NZQ7 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 2/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.32 |
| ▸ | KDM5A | P29375 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.32 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2801328 | 0.87 | TP53 (0.37) | KMT2ADHODHKDRKDM4EALDH1A1 | |
| SCHEMBL2800965 | 0.83 | DHODH (0.35) | KMT2ADHODHKDRKDM4EALDH1A1 | |
| SCHEMBL2801052 | 0.81 | ALDH1A1 (0.37) | KMT2AKDRKDM4EALDH1A1HPGD | |
| SCHEMBL2804334 | 0.79 | ALDH1A1 (0.33) | KMT2AKDRKDM4EALDH1A1HPGD | |
| SCHEMBL2802357 | 0.77 | PDE4B (0.35) | DHODHALDH1A1 | |
| SCHEMBL2803128 | 0.76 | BRAF (0.37) | KMT2AKDRKDM4EALDH1A1HPGD | |
| SCHEMBL2800426 | 0.76 | AVPR1A (0.41) | DHODHKDRKDM4EALDH1A1HPGD | |
| SCHEMBL2802251 | 0.74 | TP53 (0.36) | S1PR5DHODHKDM4EALDH1A1HPGD | |
| SCHEMBL2801503 | 0.73 | AVPR1A (0.42) | KDM4EALDH1A1HSD17B10 | |
| SCHEMBL2801151 | 0.73 | TRPA1 (0.36) | KMT2AKDM4EALDH1A1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2206714-A1 | AGENT FOR PREVENTION AND/OR TREATMENT OF SKIN DISEASES | Kyowa Hakko Kirin Co., Ltd. (JP) | 2010-07-14 | — | — | EP | disclosed |